Zero UV-Ray drying process. the key to creating literally the world's strongest Kratom.💪🍃🤟
Many people completely misunderstand the kratom leaf vein development stages. I call it a dangerous misunderstanding because Kratom is a lifesaving efficacious tool to prevent opioid overdose according to NIH.gov the National Institutes of Health and Journal of Medicine. When a plant is developing alkaloid, all of the alkaloid continues to remain in the plant the entire time. The longer the leaf has to develop the more alkaloid the leaf has. In the world of pharmaceuticals there are two paramount terms to be understood which is a Placebo effect and a Nocebo effect. Because many people believe that red vein is the vein kratom has the most alkaloid they experience a placebo effect of it working better for them. In actuality the longer a leaf has had to develop the more alkaloid that is present in the leaf. Fully Mature Vein Kratom unquestionably has the most alkaloid and it is proven by UPLC (Ultra Performance Liquid Chromatography) in an ISO 17025 certified AL2A accredited pharmaceutical laboratory testing facility. We have documented scientific proof that our kratom contains more analgesic alkaloid which means pain blocking alkaloid than any other kratom on the market. Fully mature vein contains all of the alkaloid that red vein contains and significantly higher amounts of 7OH (7-hydroxymitragynine) which is the primary analgesic alkaloid found in Kratom 17 times stronger than morphine and 30 times stronger than Mitragynine at blocking pain signals according to the National Institutes of Health and Journal of Medicine NIH.gov our kratom has an average of four times more 7OH then the market average and has tested as high as 20 times the market average.
We are the world's first kratom source to manufacture kratom with a 7OH alkaloid potency level that is 20x higher than the kratom market average 7OH content (1.000% vs 0.050%). According to NIH.gov the typical amount of 7OH (kratom's primary and most potent pain-reducing alkaloid) found in kratom is 0.050%. Our "Fully-Mature Vein Kratom" typically has around 4x times more 7OH than the kratom market average (0.20% vs 0.05%) and has tested as high as 1.00% 7OH content by total weight which is 20x times higher than the typical kratom alkaloid level! Here is a direct quote from NIH about typical kratom 7OH levels:
Kratom contains a number of indole alkaloids that are believed to be the primary contributors to its psychoactive effects. Chief among these is mitragynine (Figure Figure11), which typically constitutes 1–2% of the dry leaf mass and up to approximately two-thirds of the total alkaloid content.1,5 This compound is joined by 7-hydroxymitragynine (7-OH, Figure Figure11) in much lower concentrations, typically less than 0.05% of the dried leaf mass.1,20 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598159/#ref5
We have a third-party USA Licensed Pharmaceutical testing facility do UPLC testing on our kratom to measure the exact levels of 7-OH & Mitragynine alkaloid. Mitragynine is pretty much irrelevant because 7OH is 30x times stronger than mitragynine. 7-OH is the primary molecule that determines kratom potency, here is another direct quote from NIH.gov about 7OH (7HYDROXYMITRAGYNINE):
WAIT... First & foremost the source of this information is from the United States National Library of Medicine and National Institutes of Health and is cited with a direct link, it is not medical advice or anything like that! So, we comply with the anti-plant & anti-American health & happiness murderous FDA kratom consumption ban all our kratom is religious memorabilia so we can share & follow NIH information about kratom and 7-OH and help save American lives with this Godsend plant. Anyway, back to the NIH quote about kratom alkaloid potency:
Among these alkaloids, 7-hydroxymitragynine showed the most potent opioid effect on the electrically stimulated contraction (pD (2) = 8.38 +/- 0.12). The potency, calculated using pD (2) values, was 30 and 17-fold higher than that of mitragynine and morphine, respectively. Antagonism of naloxone on concentration-response curves for 7-hydroxymitragynine confirmed its opioid effect. These results suggest that the opioid effect of M. speciosa is mostly based on the activity of 7-hydroxymitragynine. https://pubmed.ncbi.nlm.nih.gov/15770543/
So from the United States National Library of Medicine and National Institutes of Health we can read the data showing that 7OH is the main molecule within kratom that gives its analgesia (pain blocking) ability. 7OH is to kratom what caffeine is to coffee, it’s what makes it work. Here is a bit more data about 7OH and kratom's potency from NIH:
7-Hydroxymitragynine is an agonist at the μ-opioid receptor[3]with a potency, calculated using pD (2) values, that is 30 fold higher than that of mitragynine and 17 fold higher than that of morphine, respectively.[4] As a partial agonist at this receptor[5] it causes significantly milder side effects than morphine,[6] like constipation, development of tolerance and withdrawal syndrome upon abstinence.[2] In murine models, the extracted alkaloids of the Kratom plant are shown to cause an insignificant amount of drug induced respiratory depression, unlike full μ-opioid agonists.[7] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601368/
Here is one more Godsend bit of information about 7-OH given to us from the United States National Library of Medicine and National Institutes of Health about its amazing ability to greatly reduce my personal pain without causing the much too common lethal side effect of respiratory depression and other common side effects from painkillers:
In a previous report, both mitragynine and 7-OH were found to display G protein-biased agonism at the mu-opioid receptor,8 a concept which gained significance in drug discovery over the recent years, where G protein-biased mu-opioid receptor agonists may deliver the desired analgesia without the unwanted side effects.
Overall, this work provides knowledge that can be used for creating novel pain therapeutics based on kratom. The Mitragynine alkaloid scaffold represents an attractive framework for the development of functionally biased opioid modulators, which may exhibit improved therapeutic profiles as analgesic drugs. In particular, respiratory safety is of major importance to clinicians due to the risk for fatal outcomes and because respiratory suppression is the primary cause of opioid-related overdose mortality. The pharmacological profile of 7-OH as a partial G protein-biased agonist at the mu-opioid receptor would signify a desirable, wide analgesia-respiratory depression therapeutic window. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598155/
There is so much data from our United States National Library of Medicine and National Institutes of Health about 7OH and it is all way way worth reading. I greatly advise you to read and follow the information about 7OH from NIH, haha it rhymes.
KRATOM KINGDOM is the world’s most potent kratom with the highest 7-OH levels, it’s not opinion, it is a literal scientific fact proven by third party UPLC lab testing! KRATOM KINGDOM IS LITERALLY THE WORLD'S STRONGEST KRATOM! 🙌🍃💪❤️
7-OH is to kratom what caffeine is to coffee. it's what makes it work & why our kratom is the best 💪🍃🤟
A nocebo effect is said to occur when negative expectations of the patient regarding a treatment cause the treatment to have a more negative effect than it otherwise would have.[1][2] For example, when a patient anticipates a side effect of a medication, they can experience that effect even if the "medication" is actually an inert substance.[1] The complementary concept, the placebo effect, is said to occur when positive expectations improve an outcome. The effect is also said to occur in someone who falls ill owing to the erroneous belief that they were exposed to a toxin, or to a physical phenomenon they believe is harmful, such as EM radiation.[3]
A placebo (/pləˈsiːboʊ/ plə-SEE-boh) is a substance or treatment which is designed to have no therapeutic value.[1] Common placebos include inert tablets (like sugar pills), inert injections (like saline), sham surgery,[2] and other procedures.[3]In general, placebos can affect how patients perceive their condition and encourage the body's chemical processes for relieving pain[4] and a few other symptoms,[5] but have no impact on the disease itself.[6][4] Improvements that patients experience after being treated with a placebo can also be due to unrelated factors, such as regression to the mean (a statistical effect where an unusually high or low measurement is likely to be followed by a less extreme one).[4] The use of placebos in clinical medicine raises ethical concerns, especially if they are disguised as an active treatment, as this introduces dishonesty into the doctor–patient relationship and bypasses informed consent.[7] While it was once assumed that this deception was necessary for placebos to have any effect, there is some evidence that placebos may have subjective effects even when the patient is aware that the treatment is a placebo (known as open-label placebo).[8]In drug testing and medical research, a placebo can be made to resemble an active medication or therapy so that it functions as a control; this is to prevent the recipient or others from knowing (with their consent) whether a treatment is active or inactive, as expectations about efficacy can influence results.[9][10] In a placebo-controlled clinical trial any change in the control group is known as the placebo response, and the difference between this and the result of no treatment is the placebo effect.[11] Some researchers now recommend comparing the experimental treatment with an existing treatment when possible, instead of a placebo.[12]The idea of a placebo effect—a therapeutic outcome derived from an inert treatment—was discussed in 18th century psychology,[13] but became more prominent in the 20th century. An influential 1955 study entitled The Powerful Placebo firmly established the idea that placebo effects were clinically important,[14] and were a result of the brain's role in physical health. A 1997 reassessment found no evidence of any placebo effect in the source data, as the study had not accounted for regression to the mean.[15][16]
Nothing on this website is medical advice. It is all done for personal reasons that have saved my life as I seek to pay forward and help stop the growth of America's opioid overdose epidemic.
PLEASE HELP SAVE LIVES & SHARE THIS: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598155/
1 AMERICAN IS KILLED EVERY 33 MINUTES BY IBUPROFEN & OVER THE COUNTER NSAID
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MAN-MADE OPIOIDS KILL MORE THAN 47,000 AMERICANS ANNUALLY
IBUPROFEN & NSAIDs KILL 15,600 AMERICANS ANNUALLY
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